
Valerian Root Extract – 0.8% Valerenic Acids by HPLC

Valerian Root Extract – 0.8% Valerenic Acids by HPLC
- Mechotech: Advanced Solutions Valerian Root Extract – 0.8% Valerenic Acids by HPLC Home Valerian Root Extract Valerian Root Extract – 0.8% Valerenic Acids by HPLC Valerian ( Valeriana officinalis ) root has a long history of traditional use for mild relaxation, sleep support, and calming formulations. Mechotech’s Valerian Root Extract is standardized to 0.8% Valerenic Acids by HPLC to ensure consistent activity in nutraceutical and herbal products. Extraction Process Freshly harvested.
Mechotech designs and manufactures the Valerian Root Extract – 0.8% Valerenic Acids by HPLC as a turnkey solution with SS 316L construction, integrated solvent recovery, and full documentation support. Our plant engineering team ensures optimal process parameters for maximum yield and quality compliance with FSSAI, WHO-GMP, and pharmaceutical-grade specifications.
Manufacturing Process
Raw Material Authentication & Preparation
Dried Valerian Root Extract – 0.8% Valerenic Acids by HPLC plant material is authenticated by HPTLC or macroscopic identification and tested for moisture content (target below 10%). Material is cleaned, milled to 0.5–2 mm particle size to maximise solvent contact surface area before extraction.
Solvent Extraction
Milled Valerian Root Extract – 0.8% Valerenic Acids by HPLC material is extracted with food-grade ethanol (60–95% depending on target compound polarity) or water in closed, jacketed extractors at 40–70°C for 2–6 hours. Multiple extraction cycles with fresh solvent maximise bioactive compound recovery.
Filtration
The Valerian Root Extract – 0.8% Valerenic Acids by HPLC extract (miscella) is filtered through a plate-and-frame filter press followed by cartridge polish filters (1–5 micron) to remove plant particulates and achieve pharmaceutical-grade miscella clarity before concentration.
Evaporation & Concentration
The filtered miscella is concentrated in a falling-film evaporator at 50–65°C under vacuum (50–80 mbar) to remove the bulk of the solvent. Greater than 95% solvent recovery is achieved through the condenser return system, reducing operating cost significantly.
Standardisation
The concentrated Valerian Root Extract – 0.8% Valerenic Acids by HPLC extract is analysed by HPLC for the key bioactive marker compounds. Batches are blended or adjusted to meet the declared extract specification and homogenised before drying.
Drying & Quality Control
The standardised extract is spray-dried or vacuum-dried to free-flowing powder form. Each batch undergoes full QC testing: HPLC assay, residual solvent (GC headspace), heavy metals (ICP-MS), microbial limits, and moisture before release.
Applications
- Pharmaceutical standardised herbal extracts and phytomedicines
- Nutraceutical capsule and tablet formulations
- Ayurvedic and traditional medicine preparations
- Cosmetic and personal care active ingredient supply
- Functional food and dietary supplement manufacturing
- Research and clinical study standardised extract supply
- Export to pharmaceutical ingredient buyers in regulated markets
- Herbal tinctures, syrups, and liquid extract products
Key Features
GMP-Compliant SS 316L Construction
All product-contact surfaces are fabricated in electropolished SS 316L stainless steel, meeting WHO-GMP and Schedule M requirements for botanical extract manufacturing. Designed for clean-in-place (CIP) operation between batches.
Closed-Loop Solvent Recovery (>95%)
Integrated condenser-distillation solvent recovery system achieves greater than 95% solvent return per batch, significantly reducing variable operating cost and ensuring compliance with CPCB solvent discharge regulations.
Scalable Batch Capacity
Plants are designed in standard capacities from 100 kg/batch pilot scale to 2,000+ kg/batch commercial configurations for Valerian Root Extract – 0.8% Valerenic Acids by HPLC. Modular design allows capacity expansion without replacing core equipment.
Integrated Quality Control
In-line sampling ports at each processing stage enable in-process quality monitoring. Plant design accommodates HPLC, GC, and physical testing equipment for batch release documentation required by pharmaceutical and food buyers.
Explosion-Proof Design (Solvent Zones)
All electrical equipment, motors, instruments, and fittings in solvent-handling areas are certified explosion-proof per ATEX/PESO standards, ensuring safe operation with flammable ethanol, hexane, and acetone solvents.
Frequently Asked Questions
What is Valerian Root Extract – 0.8% Valerenic Acids by HPLC and why is it commercially extracted?
What extraction method does Mechotech use for Valerian Root Extract – 0.8% Valerenic Acids by HPLC?
What production capacities are available for the Valerian Root Extract – 0.8% Valerenic Acids by HPLC?
What quality certifications apply to the Valerian Root Extract – 0.8% Valerenic Acids by HPLC?
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